Free STEP2 Exam Braindumps (page: 43)

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A pregnant woman has been taking phenytoin (Dilantin) for a seizure disorder. She is concerned that the drug will cause fetal abnormalities. Which of the following defects is the most common anomaly associated with phenytoin?

  1. atrial septal defect
  2. ventricular septal defect
  3. cleft lip/palate
  4. spina bifida
  5. hydrocephalus

Answer(s): C

Explanation:

As many as 30% of fetuses exposed to phenytoin had minor craniofacial and digital anomalies. Cleft lip/ palate, hypertelorism, broad nasal bridge, and epicanthal folds are the craniofacial anomalies observed.
Hypoplasia of the distal phalanges and nails are the digital anomalies. In addition, these infants may have growth and cognitive deficiencies. Trimethadione, another anticonvulsant, causes similar anomalies. Spina bifida occurs in 12% of infants whose mothers took valproic acid during pregnancy.



When counseling pregnant women about the dangers of drug use during pregnancy, they should be told that the rate of spontaneous major malformations in newborns is what?

  1. less than 1%
  2. 24%
  3. 68%
  4. 1012%
  5. more than 12%

Answer(s): B

Explanation:

Approximately 3% of live born infants have a major congenital anomaly detected at birth.The incidence increases to 67% later in childhood. Chromosomal and single-gene defects account for 10 25% of human malformations. Fetal infections (35%), maternal disease (4%), and drugs and medications (<1%) account for the remaining recognized causes of human malformations. Sixty-five to seventy-five percent of malformations have an unknown or multifactorial etiology



A 34-year-old woman just delivered a 4100-g boy after a 15-hour labor, including a 21/2-hour second stage. During the repair of a midline episiotomy, there is a marked increase in the amount of vaginal bleeding.

Which of the following is the most common cause of immediate postpartum hemorrhage?

  1. retained placental fragments
  2. uterine atony
  3. cervical laceration
  4. vaginal laceration
  5. disseminated intravascular coagulation

Answer(s): B

Explanation:

The main mechanism by which hemostasis is achieved following delivery is contraction of the myometrium to compress the uterine vessels that had been supplying the placenta. Lack of effective myometrial contraction (i.e., uterine atony) is the major cause of postpartum hemorrhage. If the uterus is found to be firmly contracted, then other factors, such as cervical or vaginal lacerations or a coagulopathy, must be sought.



A 34-year-old woman just delivered a 4100-g boy after a 15-hour labor, including a 21/2-hour second stage. During the repair of a midline episiotomy, there is a marked increase in the amount of vaginal bleeding.

Which of the following is the best immediate management of the probable cause of this postpartum hemorrhage?

  1. massage and compression of the uterine fundus
  2. intravenous administration of 20 units of oxytocin
  3. abdominal hysterectomy
  4. uterine artery embolization
  5. hypogastric artery ligation

Answer(s): A

Explanation:

Immediate management is bimanual massage and compression of the uterine fundus by placing one fist into the anterior vaginal fornix and the other hand abdominally posterior to the uterus. The uterine massage is often enough to cause myometrial contractions and slowing of the bleeding. Oxytocin or an ergot alkaloid (e.g., methylergonovine) should then be administered if bimanual massage of the uterus is ineffective.
Insertion of a gauze pack is never indicated because it is rarely effective. It may actually worsen the bleeding by preventing contraction of the myometrium. Persistent bleeding from the uterus despite these measures may indicate uterine rupture, retained placental fragments, or placenta accreta. If a careful curettage of the uterine lining fails to remove any placental fragments and decrease uterine bleeding, hypogastric artery ligation or a hysterectomy must be considered.



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Alken commented on January 04, 2025
No comments yet Still watching the pattern of exam
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Allen commented on January 04, 2025
Nice approach
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