Cisco
CompTIA
ISC
EC-Council
EXIN
Fortinet
ITIL
Juniper
Microsoft
VMware
Avaya
SAP
Google
NVIDIA
Salesforce
Amazon
Palo Alto Networks
ISC2
Splunk
ServiceNow
All Vendors
  2. Home
  3. Exams
  4. MRCPUK
  5. SEND

MRCPUK SEND Exam
SEND - Endocrinology and Diabetes (Specialty Certificate Examination) (Page 13 )

Updated On: 9-Feb-2026
Page 8 of 41
PDF with 200 Questions

A 56-year-old man with a 5-year history of type 2 diabetes mellitus was worried about developing a foot ulcer. Which clinical feature, if present, best predicts the development of a foot ulcer in a patient with diabetes?

  1. absent foot pulses
  2. absent sensation to a monofilament
  3. history of a previous foot ulcer
  4. inability to perform own foot care
  5. vibration perception threshold >25v

Answer(s): C



A 23-year-old man presented with a history of discomfort with his gender for as long as he could remember. He believed he was transsexual.
What element of further history would most strongly support his self-diagnosis?

  1. a long-standing intense wish to make his body conform to that of the preferred gender
  2. conscious and absolute rejection of his sexual orientation as socially unacceptable
  3. seeking medical rationalisation for sexuality through genital surgery
  4. sexual excitement by cross-dressing
  5. the presence of gender somatic delusions that emerge and strengthen with time

Answer(s): A



A 17-year-old boy with type 1 diabetes mellitus was admitted with diabetic ketoacidosis precipitated by a recent viral illness.
Investigations on admission:

-random plasma glucose15.0 mmol/L arterial blood gases, breathing air:
-pH7.07 (7.35–7.45)
-H+85 nmol/L (35–45)
-Investigations after initial treatment with fluids, insulin and potassium 7 h after admission: random plasma glucose4.0 mmol/L serum bicarbonate10 mmol/L (20–28)

At this stage, he was being given infusions of insulin (1 U/h) and glucose 5% (100 mL/h). What is the most appropriate next step in management?

  1. continue current regimen
  2. continue current regimen but encourage oral carbohydrate intake
  3. continue insulin infusion and change glucose to a higher concentration
  4. give intravenous sodium bicarbonate
  5. stop insulin infusion if glucose falls any further, then repeat plasma glucose in 15 min

Answer(s): C



A 56-year-old man was referred urgently by an ophthalmologist after presenting with a 6-month history of deteriorating vision. The patient had a 40 pack-year smoking history. Before his vision problem, he had never visited his general practitioner.

Investigations:
-serum cortisol (09.00 h)389 nmol/L (200–700) serum testosterone8.6 nmol/L (9.0–35.0)
-plasma follicle-stimulating hormone2.1 U/L (1.0–7.0) plasma luteinising hormone2.4 U/L (1.0–10.0)
-serum prolactin896 mU/L (<360)
-serum thyroid-stimulating hormone1.4 mU/L (0.4–5.0) MR scan of pituitarysee image



What is the most likely diagnosis?

  1. craniopharyngioma
  2. meningioma
  3. non-functioning adenoma
  4. prolactinoma
  5. Rathke’s cyst

Answer(s): B



An 18-year-old man presented with delayed puberty.
On examination, he had a high arched palate. His sense of smell was intact, and he had a family history of pubertal delay. Kallman’s syndrome was suspected.

Investigations:
-serum testosterone0.3 nmol/L (9.0–35.0)
-serum follicle-stimulating hormone1.0 U/L (1.0–7.0) serum luteinising hormone1.0 U/L (1.0–10.0)
-bone age15 years

What further clinical finding would most strongly support the diagnosis of Kallman’s syndrome?

  1. bimanual synkinesia (mirror movements)
  2. eunuchoid habitus
  3. night blindness
  4. short stature
  5. testes 6 mL bilaterally

Answer(s): A






Post your Comments and Discuss MRCPUK SEND exam prep with other Community members:

Join the SEND Discussion