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Foreign Pharmacy Graduate Equivalency Examination Questions 176–180 (page: 37)

Updated On: 9-Feb-2026

Resistance is the major problem with penicillins due to ability of bacteria to breakdown the lactam ring of penicillin and inactivates the drug. To overcome these problem penicillins can be administrated together with -lactamase inhibitors.
Examples of -lactamase inhibitors is/are:

I- Clavulanic acid
II- Sulbactam
III- Tazobactam

  1. I only
  2. III only
  3. I and II only
  4. II and III only
  5. All are correct

Answer(s): E



Correct statements regarding CEPHALOSPORINS include:

I- Bactericidal antimicrobial
II- Derivated from natural source: Cephalosporium acremonium
III- Broad-spectrum agent

  1. I only
  2. III only
  3. I and II only
  4. II and III only
  5. All are correct

Answer(s): D



Example of fourth generation cephalosporin includes:

  1. Ceftriaxone
  2. Cefipime
  3. Cefixime
  4. Cefotaxime
  5. Cefoxitin

Answer(s): B



Correct statement regarding the mechanism of action of Vancomycin may include:

  1. Inhibit release of tRNA bound to peptyl site after peptide bond formation
  2. Inhibit peptide bound formation between acylaminoacids bound to the peptyl and acceptor site
  3. Inhibit stage II of cell wall synthesis preventing polymerization of the linear peptideoglycan
  4. Inhibit DNA gyrase in the bacteria
  5. Bind to ergosterol from pores resulting in linkage of cellular

Answer(s): C



Which of the following is one of the most common side effects of vancomycin?

  1. Ototoxicity
  2. Disulfiram like side effect
  3. Diarrhea
  4. Weight gain
  5. Hallucinations

Answer(s): A



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