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National Council Licensure Examination - NCLEX-RN Questions 426–428 (page: 172)

Updated On: 9-Feb-2026

Based on your knowledge of genetic inheritance, which of these statements is true for autosomal recessive genetic disorders?

  1. Heterozygotes are affected.
  2. The disorder is always carried on the X chromosome.
  3. Only females are affected.
  4. Two affected parents always have affected children.

Answer(s): D

Explanation:

(A) The term heterozygote refers to an individual with one normal and one mutant allele at a given locus on a pair of homologous chromosomes. An individual who is heterozygous for the abnormal gene does not manifest obvious symptoms. (B) Disorders carried on either the X or Y sex chromosome are referred to as sex-linked recessive. (C) Either sex may be affected by autosomal recessive genetic disorders because the responsible allele can be on any one of the 46 chromosomes. (D) If both parents are affected by the disorder and are not just carriers, then all their children would manifest the same disorder.



Based on your knowledge of genetic inheritance, which of these statements is true for autosomal recessive genetic disorders?

  1. Heterozygotes are affected.
  2. The disorder is always carried on the X chromosome.
  3. Only females are affected.
  4. Two affected parents always have affected children.

Answer(s): D

Explanation:

(A) The term heterozygote refers to an individual with one normal and one mutant allele at a given locus on a pair of homologous chromosomes. An individual who is heterozygous for the abnormal gene does not manifest obvious symptoms. (B) Disorders carried on either the X or Y sex chromosome are referred to as sex-linked recessive. (C) Either sex may be affected by autosomal recessive genetic disorders because the responsible allele can be on any one of the 46 chromosomes. (D) If both parents are affected by the disorder and are not just carriers, then all their children would manifest the same disorder.



The physician prescribes phenytoin (Dilantin) for a client with seizure disorders. Phenytoin can only be mixed with which of the following solutions?

  1. Ringer's lactate
  2. D5 in water
  3. D5 with Ringer's lactate
  4. Normal saline

Answer(s): D

Explanation:

(A) Phenytoin will precipitate if mixed with Ringer's lactate and should not be administered. (B, C) Phenytoin will precipitate if mixed with D5 in Ringer's lactate and should not be administered. (D) Phenytoin is compatible only with normal saline and should be mixed only with normal saline for administration.



The physician prescribes phenytoin (Dilantin) for a client with seizure disorders. Phenytoin can only be mixed with which of the following solutions?

  1. Ringer's lactate
  2. D5 in water
  3. D5 with Ringer's lactate
  4. Normal saline

Answer(s): D

Explanation:

(A) Phenytoin will precipitate if mixed with Ringer's lactate and should not be administered. (B, C) Phenytoin will precipitate if mixed with D5 in Ringer's lactate and should not be administered. (D) Phenytoin is compatible only with normal saline and should be mixed only with normal saline for administration.



A client is hyperactive and not sleeping. She will not remain at the table during mealtime. She is getting very limited calories and is using a lot of energy in her hyperactive state. The most therapeutic nursing action is to:

  1. Insist that she remain at the table and eat a balanced diet.
  2. Order a high-calorie diet with supplements.
  3. Provide nutritious finger foods several times a day.
  4. Offer to go to the dining room with her and allow her to open the food and inspect what she eats.

Answer(s): C

Explanation:

(A) The client is not able to sit for long periods. Forcing her to remain at the table will increase her anxiety and cause her to become hostile. (B) This action will not ensure that the client eats what is ordered. Dietary orders are not within the nurse's scope of practice. (C) Providing finger foods increases the likelihood of eating for hyperactive persons. They may be eating "on the run." (D) These clients are not suspicious of the food or insecure in moving about the unit alone.



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