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Foreign Pharmacy Graduate Equivalency Examination Questions 11–15 (page: 4)

Updated On: 9-Feb-2026

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QUESTION: 11 Topic: 1, Volume A

Which of the following enzymes could metabolize ethanol?

Cytochrome P450
Alcohol Dehydrogenase
Glucuronyl Transferase
Sulfotransferase
All of the above

Answer(s): E

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QUESTION: 12 Topic: 1, Volume A

Which of the following are similarities between Cytochrome P450 and MAO?

Both add oxygen from O2 to substrates and also form water
Both carry out direct heteroatom oxidations
Both carry out oxidative deaminations
Both carry out N-dealkylations
All of the above

Answer(s): C

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QUESTION: 13 Topic: 1, Volume A

What would be the preferred route of metabolism of succinyl choline?

Ester hydrolysis
N-oxidation
Glucuronide conjugation
A & B
All of the above

Answer(s): C

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QUESTION: 14 Topic: 1, Volume A

Which of the following causes the smallest change in solubility?

Hydroxylation
Glucuronidation
Sulfation
Glutathione conjugation

Answer(s): A

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QUESTION: 15 Topic: 1, Volume A

Cigarette smoke causes an increase in levels of CYP1A isozymes. Theophylline is primarily metabolized by the CYP1A system. What would happen to theophylline clearance for an asthmatic patient in hospital who could not smoke?

No change
Increase
Decrease

Answer(s): C

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