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Foreign Pharmacy Graduate Equivalency Examination Questions 1–5 (page: 2)

Updated On: 9-Feb-2026

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QUESTION: 1 Topic: 1, Volume A

In a zero order elimination process, which of the following is true?

The removal of drug is independent of drug concentration
Cl = Elimination rate/Cp
t1/2 = .7VD/Cl
All are true

Answer(s): A

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QUESTION: 2 Topic: 1, Volume A

For highly polar drugs (e.g. mannitol) what primarily determines elimination rate?

Excretion rate
Metabolism rate
Absorption rate
Distribution rate
All of the above

Answer(s): A

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QUESTION: 3 Topic: 1, Volume A

Bioavailability is related to which of the following parameters, according to the equation
F = 1 - E

Excretion
Elimination
Extraction Ratio
Enterohepatic Recycling

Answer(s): C

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QUESTION: 4 Topic: 1, Volume A

For the majority of drugs, which of the following equations correctly defines clearance?

Cl = Elimination rate/Cp
Cl = QxE
Cl = .7VD/t1/2
All are correct

Answer(s): D

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QUESTION: 5 Topic: 1, Volume A

How much of a 10 mg dose of morphine reaches the systemic circulation given F = .24?

24mg
0.24 mg
2.4 mg
4.1 mg

Answer(s): C

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