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North American Pharmacist Licensure Examination Questions 46–50 (page: 11)

Updated On: 9-Feb-2026

An order is received for heparin 18 units per kg per hour on a patient whose weight is 125lb. The IV bag comes as a concentration of 50 units /mL. Calculate the infusion rate in terms of mL/hr.

  1. 5.15 mls/hr
  2. 10.23 mls/hr
  3. 40.9 mls/hr
  4. 20.45 mls/hr
  5. 18 mls/hr

Answer(s): D

Explanation:

125 lb =56Kg, 56Kg × [18 units/ 1 kg] = 1022.72 units/hr, 1022.72 units × [1 mL/50 units] = 20.45 mL/hr



According to the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to ReduceAtherosclerotic Cardiovascular Risk in Adults, which of the following LDL cholesterol thresholds is an indication for high- intensity statin therapy?

  1. ≥ 100 mg/dL
  2. ≥ 130 mg/dL
  3. ≥ 190 mg/dL
  4. ≥ 200 mg/dL
  5. ≥ 150 mg/dL

Answer(s): C

Explanation:

Statin therapy should be used as treatment in adults with primary LDL–C ≥190 mg/dL and age over 21 years. Unless contraindicated, high-intensity statin therapy should be used.



Injectable Sulfamethoxazole/Trimethoprim comes as 400mg/80mg/5ml. Physician requests you to dose a Sulfamethoxazole/Trimethoprim intravenously for PCP. You know the dose is 15mg/kg/day (based on TMP component) divided q6h.
How many milliliters of Sulfamethoxazole/Trimethoprim of 400mg/80mg/5ml would you need for single dose? Patient weighs 80kg.

  1. 18.75 mL
  2. 75 mL
  3. 15 mL
  4. 50 mL
  5. 16.5 mL

Answer(s): A

Explanation:

80kg person = 15mg/kg/day = 1200mg/day 80mg /5ml = 1200mg/X X= 75mL/day / 4 doses = 18.75 mL per dose



Which of the following is/are appropriate for pseudomonas skin/soft tissue infections?

  1. Ertapenem
  2. Cefepime
  3. Ceftaroline
  4. Cefazolin
  5. Vancomycin

Answer(s): B

Explanation:

Ceftaroline covers MRSA, but it does not cover pseudomonas. Ertapenem does not cover pseudomonas. Cefazolin does not cover MRSA nor Pseudomonas. Cefepime has pseudomonas coverage. Vancomycin does not cover gram negative bacteria.



What is the weight of 1000 ml of serum protein whose specific gravity is 1.27?

  1. 1270 gm
  2. 127mg
  3. 12.7mg
  4. 12.7gm
  5. 1.27gm

Answer(s): A

Explanation:

SG= weight/mL, 1.27 = x/1000ml, x = 1270gm



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