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North American Pharmacist Licensure Examination Questions 56–60 (page: 13)

Updated On: 9-Feb-2026

Which of the following medication may increase LDL?

  1. Lisinopril
  2. Hydrochlorothiazide
  3. Diltiazem
  4. Metoprolol
  5. Amlodipine

Answer(s): B

Explanation:

LDL can be elevated by diuretics, cyclosporine, glucocorticoids, and amiodarone.



In Normal distribution, what percentage of the sample is found within 2 standard deviation of the mean?

  1. 68%
  2. 95%
  3. 99%
  4. 100%
  5. 72%

Answer(s): B

Explanation:

In a normal distribution sample, within 1 standard deviation 68% of the sample falls within 1 standard deviation, 95% within 2 standard deviations, and 99.7% within 3 standard deviations of the mean.


Reference:

http://www.bmj.com/about-bmj/resources-readers/publications/statistics-square-one



A Physician orders amiodarone 1 mg/min for six hours, then 0.5 mg/min thereafter. The patient’s weight is 156 lbs. The concentration of the IV bag comes as 1.8 mg per ml. Calculate the infusion rate in mL/hr.

  1. 33.33mls/hr then /16.67mls/hr
  2. 60mls/hr then 30mls/hr
  3. 30mls/hr then 15mls/hr
  4. 16.67mls/hr then 8.3mls/hr
  5. 8.3mls/hr then 4.15mls/hr

Answer(s): A

Explanation:

[1 mg/ 1 min] × 60min= 60mg/hr. 60 mg/hr × [1 mL/ 1.8 mg] = 33.33 mL/hr 0.5 mg/min × [60 min/ 1 hr] = 30 mg/hr 30 mg/hr × [1 mL/1.8 mg] = 16.67 mL/hr Infusion rates: 33.33 mL/hr for 6 hours, then 16.67 mL/hr



Which of the following medication can lower seizures threshold?

  1. Bupropion
  2. Tramadol
  3. Clozapine
  4. Thiothixene
  5. All of the above can lower seizure threshold

Answer(s): E

Explanation:

Seizure threshold can be lowered by bupropion, chlorpromazine, clozapine, maprotiline, olanzapine, thioridazine, thiothixene, and tramadol.



Which of the following medication should be avoided in patients with heart failure?

  1. Cilostazol
  2. Pioglitazone
  3. Naproxen
  4. Celebrex
  5. All of the above

Answer(s): E

Explanation:

Patients with heart failure should avoid taking NSAIDs (which includes naproxen), COX-2 inhibitors, nondihydropyridine calcium channel blockers (for reduced EF), thiazolidinediones (which includes pioglitazone), cilostazol, and dronedarone (for severe or recently decompensated heart failure).



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